TABLE 2.
Solute Carrier (SLC) Gene Families of Small-Molecule Transporters
| Family | Substrate Specificity | Abbreviations |
|---|---|---|
| SLC1 | Acidic amino acid transporter | EEAT |
| ASC small neutral amino acid transporter | ASCT | |
| SLC2 | Glucose transporter | GLUT |
| H+-myo-inositol transporter | HMIT | |
| SLC3 | Heavy chain of heterodimeric amino acid transporters | 4F2hc |
| SLC4 | Bicarbonate/carbonate exchangers and Na+ coupled transporters | AE, NBC |
| SLC5 | Sodium/substrate cotransporters (glucose, choline) | SGLT, CHT |
| SLC6 | Neurotransmitter transporters (GABA, glycine, taurine, monoamines, creatine) | GAT, TAUT |
| SLC7 | Cationic amino acid transporter | CAT |
| Light chain of amino acid transporters | LAT | |
| SLC8 | Sodium/calcium exchanger | NCX |
| SLC9 | Sodium/proton exchanger | NHE |
| SLC10 | Sodium/bile salt cotransporter | NTCP, ASBT |
| SLC11 | Natural resistance-associated macrophage protein | NRAMP |
| Divalent metal-ion transporter | DMT | |
| SLC12 | Potassium/chloride cotransporter | KCC |
| SLC13 | Sodium/sulphate cotransporter | NaS |
| Sodium/dicarboxylate transporter | NaDC | |
| SLC14 | Urea transporter | UT |
| SLC15 | Proton peptide transporter | PEPT |
| SLC16 | Monocarboxylic acid transporter (lactate, pyruvate, ketone bodies) | MCT |
| SLC17 | Vesicular glutamic acid transporter | VGLUT |
| SLC18 | Vesicular amine transporter | VAT |
| SLC19 | Vitamin transporters (folic acid, thiamine) | THTR |
| SLC20 | Sodium-phosphate cotransporters | Pit |
| SLC21 | Organic anion transporters | OATP |
| SLC22 | Organic cation transporters | OCTN, OAT |
| SLC23 | Sodium/ascorbic acid transporter | SVCT |
| SLC24 | Sodium/calcium-potassium exchanger | NCKX |
| SLC25 | Mitochondrial carriers | MC |
| SLC26 | Anion exchangers | CFTR |
| SLC27 | Fatty acid transport proteins | FATP |
| SLC28 | Sodium dependent nucleoside transporters | CNT |
| SLC29 | Equilibrative nucleoside transporters | ENT |
| SLC30 | Zinc efflux transporters | ZNT |
| SLC31 | Copper efflux transporters | CTR |
| SLC32 | Vesicular neurotransmitter transporters | VIAAT, VGAT |
| SLC33 | Acetyl-CoA transporters | AT |
| SLC34 | Sodium/phosphate cotransporters | NaPi |
| SLC35 | Nucleotide sugar transporters | UGT |
| SLC36 | Lysosomal amino acid transporters | LYAAT |
| SLC37 | Glucose-6-phosphate transporter | G6PT |
| SLC38 | Sodium coupled neutral amino acid transporters | SNAT |
| SLC39 | Metal ion transporters | ZIP |
| SLC40 | Iron efflux transporter | MTP |