Table 2.

Study Characteristics.

Author,Year	Surgery	Subjects (control/intervention/[intervention])	Glucocorticoid/timing	Equivalent dexamethasone dose (mg) http://clincalc.com/Corticosteroids/	Anaesthesia	Pre-op analgesia	Post-op analgesia	Followup	Age (Mean)
Backes JR et al. [9]	TKA or THA	N = 120 (37/41/42)	Dexamethasone 10 mg IV/immediately prior to surgery; third group additional dose 24 h post-op	10	General	Oxycodone ER, celecoxib	PCA (dilaudid)x24 h, Oxycodone, hydrocodone/acetaminophen and/or dilaudid TKA patients − intra-articular pain pump (bupivicaine), celecoxib	24 weeks	66
Lunn TH et al. [10]	TKA	N = 48 (24/24)	Methylprednisolone 125 mg IV/immediatley prior to surgery	25	Spinal	Gabapentin, acetaminophen, celecoxib	Periarticular injection (ropivacaine, epinephrine), celecoxib, acetaminophen, gabapentin, sufentanil in PACU, oxycodone	30 days	66.5
Lunn TH et al. [11]	THA	N = 48 (24/24)	Methylprednisolone 125 mg IV/immediatley prior to surgery	25	Spinal	Gabapentin, acetaminophen, celecoxib	Celecoxib, acetaminophen, gabapentin, sufentanil in PACU, morphine	30 days	66
Koh IJ et al. [12]	TKA	N = 291 (145/146)	Dexamethasone 10 mg IV/one hour prior to surgery	10	spinal, continuous femoral nerve block	Pregabalin, oxycodone ER, celecoxib, acetaminophen	Periarticular injection (ropivacaine, morphine, ketorolac, epinephrine, cefuroxime), PCA (fentanyl), continuous femoral nerve block, celecoxib, pregabalin, acetaminophen, ketoprofen	1 year	72
Mathiesen O et al. [13]	THA	N = 126 (42/42/42)	Dexamethasone 8 mg IV/immediately prior to surgery	8	Spinal	Acetaminophen	PCA (morphine), acetaminophen	24 h	67
Kardash KJ et al. [14]	THA	N = 50 (25/25)	Dexamethsone 40 mg IV/immediately prior to surgery	40	Spinal	None	PCA (morphine), acetaminophen, ibuprofen	1 month	69