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Comparison of the external aldimine vs. internal aldimine in GabR. External aldimine Schiff bases (magenta and cyan), internal aldimine Schiff base with K312 (gray), and Y281 are shown in stick form. Labels and carbon atoms for internal aldimine (PDB code ID 4N0B) are in black and gray, respectively. Labels and carbon atoms for the Eb/O–PLP–GABA complex are in magenta. Labels and carbon atoms for the Eb/O–PLP–AFPA complex are in cyan.
