Fig. 1.

Mice lacking RelB develop splenomegaly and myeloid hyperplasia. (A) Splenocyte numbers in 3- and 9-wk-old WT and Relb^−/− mice. Each dot represents a biological replicate from four independent experiments. (B) Representative flow cytometry analysis of CD11b⁺ splenocytes from WT and Relb^−/− mice. Data are representative of three independent experiments. (C) Microscopy of WT and Relb^−/− splenic Ly-6G⁺ PMNs stained with Wright–Giemsa stain. (Scale bars: 10 µm.) n.s., not significant. ****P < 0.0001.