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. 2017 Mar 29;114(15):E3110–E3118. doi: 10.1073/pnas.1619302114

Fig. S4.

Fig. S4.

AuNRs-PPTT efficiently inhibits cell viability and induces apoptosis (in vitro). (A) Cell viabilities of five HNSCC cell lines under treatment with various concentrations of small AuNR for 2 h followed by 2 W/cm2 NIR laser power for 2 min. Seventy-two hours after laser treatment, cell viability was analyzed by SRB assay. The percentage of cell viability was then calculated based on the absorbance values relative to the nontreated samples. Error bars are mean ± SD from three independent experiments. (B) Cell viability analysis as above of MDA686TU cells 72 h after treatment with AuNRs@PEG-PPTT and AuNRs@RF-PPTT (error bars are mean ± SD from three independent experiments). (C) Apoptosis/necrosis assay of cells treated with PPTT under different conditions. Q1, necrosis cells; Q2+Q3, apoptosis cells; and Q4, normal cells. For comparison with other studies, 5 nM = 1 OD for small AuNRs (35).