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. 2017 Apr 11;12:758–769. doi: 10.1016/j.redox.2017.04.016

Table 2.

Hydrogen peroxide elimination ([H2O2]=5 μM) and toxicity. Cell cultures: embryonic stem cells (ESCs), their differentiated progeny cells (difESCs) and endometrial mesenchymal stem cells (eMSCs).

Cells
Parameter ESCs difESCs eMSCs
kcell, s−1 cell−1 L 3.0±0.5×10–12(N=5) 16±2×10–12 (N=4) 10±1×10–12 (N=4)
kprot, s−1 g−1 L 3.7±0.6×10−2 (N=5) 4.7±0.5×10−2 (N=4) 2.0±0.2×10−2 (N=4)
LD50cell, pmole/cell 1.0±0.3 (N=3) 11±1 (N=2)
LD50prot, mmole/protein g 12±4 (N=3) 20±2 (N=2)

Notations: kcell and kprot, first-order rate constants for the external H2O2 removal quantified on the per-cell, or per-protein basis, correspondingly; LD50cell and LD50prot, cytotoxic thresholds assessed as H2O2 dose which resulted in 50% cell death and estimated either in mole-per-cell, or mole-per-protein units, correspondingly.