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. 2013 May 24;154(9):3054–3066. doi: 10.1210/en.2013-1097

Figure 3.

Figure 3.

The Effect of High Glucose on Oxidative Stress Response, NADH Availability, and ATP Levels. A, Schwann cells maintained at 5.6 mM normal or 25 mM high glucose for more than 8 weeks were measured for ROS formation, and after change of glucose media for 4 hours. B and D, NADH availability and ATP levels at normal and high glucose, and after change to 15 mM glucose for 48 hours. C and E, Effect of the metabolites pyruvate, lactate, and β-hydroxybutyrate ketone body (30 mM) on NADH and ATP for 48 hours. Data are represented as mean ± SEM. Means with different letters are significantly different using Bonferroni post hoc test following one-way ANOVA, P < .05.