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. Author manuscript; available in PMC: 2017 Apr 17.
Published in final edited form as: J Drug Alcohol Res. 2016 Dec 31;5:236009. doi: 10.4303/jdar/236009

Figure 1.

Figure 1

(Left panel) Discriminative stimulus effects of cocaine, mephedrone, naphyrone, MDMA, METH, and morphine in mice trained to discriminate 10 mg/kg cocaine from saline. Abscissa: SAL represents test injection of saline and TD represents administration of the cocaine training dose. Numbers refer to doses of drugs during substitution sessions, expressed as milligram per kilogram on a log scale. Ordinate: percent of total responses emitted on the cocaine-appropriate lever. (Right panel) Response rates following administration of saline, cocaine, mephedrone, naphyrone, MDMA, METH, or morphine during substitution sessions. The abscissa is as described above. Ordinate: response rates, expressed as lever presses per second. Asterisks adjacent to points indicate generalization at this dose. Errors bars depict means ±SEM. The “n = 4” designation indicates only four mice were included in the data point (responding was suppressed in one mouse at 10 mg/kg MDMA).