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A critical period for nuclear RNAi. (A) Earlier dsRNA exposure results in stronger pharyngeal silencing. Bars show SEM, n = number of animals scored. (B) Pharyngeal RNAi by heat-shock-induced GFP dsRNA requires nrde-3-dependent nuclear RNAi. Bars show SEM from three trials (P<.05). (A and B) Silencing of individual sections of the pharyngeal muscle was scored.
