Table 2. Equilibrium Constants and Forward Rate Constants (Vmax) for Each Reaction in the Model Simulation.
Equilibrium constants are all dimensionless, except for reaction 9, which has units of mM. Units for kinetic constants are mM/sec unless otherwise noted
a The literature value for this constant is 0.71 mM/s. A small adjustment was required to fit the data
b Constants of twice the literature values were assumed, due to the presence of multiple formate dehydrogenases
H4F, tetrahydrofolate; H4MPT, tetrahydromethanopterin; me-H4F, methylene-H4F; me-H4MPT, methylene-H4MPT; MFR, methanofuran; mn-H4F, methenyl-H4F; mn-H4MPT, methenyl-H4MPT; Irrev., irreversible; NA, not applicable