Figure 2. Developmental exposure to oil and gas chemicals alters folliculogenesis.
Least squared mean ± SEM for each follicle type are presented at PND21 (A–E) and PND85 (F–J). The developmental progression from PND21 to PND85 for each follicle type is presented in K–O. **, different than untreated controls (vehicle) alone at P ≤ .05 (A–J); **, different between PND21 and PND85 for a single follicle stage at P ≤ .05 (K–O); n = 8, 9, 7, 8, 5, and 10 litters for vehicle (VEH), Mix3, 30, 300, 3000, and flutamide (FLUT), respectively, at PND21; n = 9, 7, 6, 8, 5, and 8 litters for vehicle, Mix3, 30, 300, 3000, and flutamide, respectively, at PND85. Abbreviation: PND, postnatal day.