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IFIX displays altered nuclear localization and protein levels during infection with WT HSV-1. A, time course showing IFIX-GFP localization in Flp-In 293s at the indicated hpi. m.o.i.: 5, ICP27 is marker of infection. B, IFIX-GFP localization upon infection of primary HFFs stably expressing IFIX-GFP. m.o.i.: 3 was taken at 4 hpi; ICP8 is marker of infection. A and B, bar, 5 μm.
