Table IV. ROC Statistics for ELISA Verification Markers and Panels.
| Gene | AUC | p value | % Sens at 80% Spec | % Spec at 80% Sens |
|---|---|---|---|---|
| US/HIV− (22 TB− 45 TB+) | ||||
| Rv2853 | .610 | 0.1475 | 31.1 | 40.9 |
| Rv2031c | .774 | 0.0003 | 62.2 | 45.5 |
| Rv0054 | .652 | 0.0409 | 53.3 | 31.5 |
| Rv0831c | .725 | 0.0029 | 60.0 | 36.4 |
| Rv3405c | .594 | 0.2144 | 33.3 | 27.3 |
| Rv3544c | .490 | 0.8932 | 28.9 | 14.9 |
| Rv0222 | .462 | 0.6165 | 20.0 | 27.3 |
| Rv0948c | .366 | 0.0757 | 8.9 | 9.1 |
| PANEL* | .807 | <0.0001 | 64.4 | 72.7 |
| US/HIV+ (46 TB− 21 TB+) | ||||
| Rv2853 | .620 | 0.1169 | 14.3 | 47.8 |
| Rv2031c | .507 | 0.9238 | 14.3 | 15.7 |
| Rv0054 | .749 | 0.0011 | 52.4 | 56.5 |
| Rv0831c | .516 | 0.8393 | 19.0 | 28.3 |
| Rv3405c | .732 | 0.0025 | 42.9 | 71.7 |
| Rv3544c | .518 | 0.8162 | 28.6 | 19.8 |
| Rv0222 | .596 | 0.2108 | 47.6 | 19.6 |
| Rv0948c | .705 | 0.0074 | 47.6 | 37.0 |
| PANEL* | .782 | 0.0002 | 61.9 | 71.7 |
| SA/HIV− (25 TB− 13 TB+) | ||||
| Rv2853 | .546 | 0.6444 | 15.4 | 24.0 |
| Rv2031c | .712 | 0.0337 | 61.5 | 28.0 |
| Rv0054 | .697 | 0.0479 | 69.2 | 17.3 |
| Rv0831c | .917 | 0.0000 | 76.9 | 72.0 |
| Rv3405c | .702 | 0.0439 | 61.5 | 68.0 |
| Rv3544c | .622 | 0.2212 | 53.8 | 13.0 |
| Rv0222 | .831 | 0.0009 | 76.9 | 64.0 |
| Rv0948c | .705 | 0.0406 | 69.2 | 28.0 |
| PANEL* | .868 | <0.0001 | 85.3 | 84.0 |
| SA/HIV+ (24 TB− 89 TB+) | ||||
| Rv2853 | .521 | 0.7574 | 13.5 | 12.5 |
| Rv2031c | .512 | 0.8519 | 15.7 | 20.8 |
| Rv0054 | .497 | 0.9661 | 22.5 | 14.3 |
| Rv0831c | .594 | 0.1582 | 34.8 | 41.7 |
| Rv3405c | .747 | 0.0002 | 57.3 | 54.2 |
| Rv3544c | .570 | 0.2923 | 30.3 | 16.9 |
| Rv0222 | .525 | 0.7072 | 27.0 | 20.8 |
| Rv0948c | .567 | 0.3118 | 34.8 | 20.8 |
| PANEL* | .723 | 0.0008 | 53.9 | 50.0 |