Table 2.
AICDA mRNA Expression and Ig-Isotype Secretion of Peripheral Blood Mononuclear Cells from Graves' Disease Patients and Controls During Epstein–Barr Virus-Reactivation Induction
| Day 0 | Day 5 | Day 10 | Day 12 | |
|---|---|---|---|---|
| AICDA mRNAa | ||||
| Controls | 0.005 | 0.062 | 0.011 | 0.029 |
| Patients | 0.003 | 0.025 | 0.018 | 0.041 |
| p | 0.522 | 0.331 | 0.230 | 0.131 |
| Total IgG (ng/mL) | ||||
| Controls | 17.696 | 7.310 | 13.614 | 10.118 |
| Patients | 16.769 | 9.911 | 14.367 | 9.948 |
| p | 0.882 | 0.882 | 0.552 | 0.71 |
| Total IgM (ng/mL) | ||||
| Controls | 53.502 | 39.181 | 20.87 | 33.546 |
| Patients | 54.562 | 35.704 | 18.195 | 26.275 |
| p | 0.603 | 0.152 | 0.824 | 0.025b |
| Total IgE (ng/mL) | ||||
| Controls | 12.993 | 8.200 | 4.511 | 10.478 |
| Patients | 11.424 | 7.215 | 5.526 | 11.491 |
| p | 0.201 | 0.080 | 0.112 | 0.261 |
AICDA mRNA relative quantity (normalized to β-actin).
Significant.
EBV, Epstein–Barr virus.