Table 1.
Demographic and Histological Features of 61 RAS-Positive Patients With Surgical Follow-Up
| FVPTC |
FTC | MTC | ATC | Benign | Total | |||
|---|---|---|---|---|---|---|---|---|
| Encapsulated |
Infiltrative | |||||||
| Noninvasive | Invasive | |||||||
| Patients, n | 29 | 11 | 4 | 4 | 1 | 1 | 11 | 61 |
| Aspirates, n | 31 | 11 | 4 | 4 | 1 | 1 | 11 | 63 |
| Age, y | ||||||||
| Mean (range) | 39 (19–77) | 51 (19–74) | 46 (28–65) | 55 (23–73) | 76 (n/a) | 65 (n/a) | 53 (23–76) | |
| ≤45 | 17 | 3 | 2 | 2 | n/a | n/a | 4 | 28 |
| >45 | 12 | 8 | 2 | 2 | 1 | 1 | 7 | 33 |
| Gender | ||||||||
| Female | 25 | 10 | 2 | 4 | n/a | n/a | 10 | 51 |
| Male | 4 | 1 | 2 | 0 | 1 | 1 | 1 | 10 |
| Tumor | ||||||||
| Mean size, cm (range) | 1.8 (0.4–5.0) | 2.5 (0.9–4.3) | 1.25 (1.0–6.3) | 3.1 (2.1–4.0) | 3.2 | 6.5 | ||
| T1 | 18 | 4 | 3 | 0 | n/a | n/a | n/a | 25 |
| T2 | 10 | 4 | 0 | 3 | n/a | n/a | n/a | 17 |
| T3 | 1 | 2 | 1 | 1 | n/a | 1 | n/a | 6 |
| T4 | 0 | 1 | 0 | 0 | 1 | n/a | n/a | 2 |
| Lymph node status | ||||||||
| N0 | 13 | 3 | 3 | 1 | 0 | 0 | n/a | 20 |
| N1 | 0 | 2 | 0 | 0 | 1 | 0 | n/a | 3 |
| NX | 16 | 6 | 1 | 3 | 0 | 1 | n/a | 27 |
| Metastases at diagnosis | ||||||||
| MX | 29 | 10 | 4 | 4 | 1 | 1 | n/a | 49 |
| M1 | 0 | 1 | 0 | 0 | n/a | n/a | n/a | 1 |
| Laterality | ||||||||
| Unilateral | 15 | 5 | 2 | 4 | n/a | n/a | n/a | 26 |
| Bilateral | 14 | 6 | 2 | 0 | 1 | 1 | n/a | 24 |
| Extent of surgery | ||||||||
| Lobectomy | 11 | 2 | 1 | 1 | n/a | n/a | 5 | 20 |
| Total thyroidectomy | 18 | 9 | 3 | 3 | 1 | 1 | 6 | 41 |
Abbreviation: n/a, not available.