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. 2013 Jul 31;98(9):E1534–E1539. doi: 10.1210/jc.2013-1102

Figure 1.

Figure 1.

Family pedigree of women with POI. This figure shows the pedigree of the proband (arrow) and her family. Solid circles indicate the affected female family members with menopause between the ages of 29 and 35 years; open symbols represent the unaffected family members and a square with a solid circle indicates a male carrier. Available genotypes at coding position 1286 in eIF4ENIF1 are indicated below the symbols, with C/C wild-type variants and C/G wild-type and mutant variant coding for a stop codon in the protein.