Table 4.
Biochemical and Behavioral Characteristics at Baseline in Persons Who Developed Prediabetes or Diabetes (Progressors) Compared With Those Who Remained Free of Incident Dysglycemia (Nonprogressors)
| Characteristic | Progressors | Nonprogressors | P Valuea |
|---|---|---|---|
| FPG, mg/dL | 94 ± 7 | 91 ± 6 | .0027 |
| 2hrPG, mg/dL | 130 ± 27 | 121 ± 25 | .0036 |
| HbA1c, % | 5.7 ± 0.5 (39 ± 5.5 mmol/mol) | 5.5 ± 0.4 (37 ± 4.4 mmol/mol) | .0190 |
| Fasting insulin, μU/mL | 9.5 ± 7.6 | 7.3 ± 6.7 | .0075 |
| HOMA-IR | 2.26 ± 1.70 | 1.71 ± 1.47 | .0012 |
| HOMA-B | 100 ± 64 | 89 ± 71 | .0392 |
| Si-clamp, μmol/kg FFM per min−1/pmol/L | 0.116 ± 0.066 | 0.147 ± 0.064 | .0002 |
| AIR, μU/mL | 81 ± 74 | 88 ± 74 | .8378 |
| AIR adjusted for Si-clampb | 54 ± 1.0 | 68 ± 1.0 | .0222 |
| Disposition index | 45.1 ± 31.1 | 63.9 ± 50.2 | .0032 |
| Total cholesterol, mg/dL | 181 ± 34 | 176 ± 32 | .2095 |
| LDL cholesterol, mg/dL | 111 ± 30 | 103 ± 28 | .0260 |
| HDL cholesterol, mg/dL | 49 ± 12 | 54 ± 14 | .0022 |
| Triglycerides, mg/dL | 104 ± 55 | 91 ± 54 | .1688 |
| hsCRP, mg/L | 4.3 ± 6.7 | 3.5 ± 5.4 | .0310 |
| Adiponectin, μg/mL | 8.53 ± 4.35 | 9.85 ± 5.68 | .0650 |
| Food habits score | 2.57± .49 | 2.56± .52 | .8900 |
| Physical activity, MET h/wk | 14.5 ± 24.3 | 20.8 ± 35.9 | .0709 |
The ± values are means ± SD except as noted. Si-clamp had 203 subjects (103 black, 100 white). To convert the values for glucose to millimoles per liter, multiply by 0.0555. To convert the values for insulin to picomoles per liter, multiply by 7.175. To convert the values for triglycerides to millimoles per liter, multiply by 0.01129. To convert the values for cholesterol to millimoles per liter, multiply by 0.02586.
a
Adjusted for age and sex.
b
Least square means ± SE.