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. 2014 Aug 27;99(10):3561–3569. doi: 10.1210/jc.2014-1413

Table 4.

Indications for Parathyroid Surgery During Monitoring

Measurement 2013
Serum calcium (>upper limit of normal) >1 mg/dL (>0.25 mmol/L)
Skeletal A. T-score <−2.5 at lumbar spine, total hip, femoral neck, or distal 1/3 radius; or a significant reduction in BMDa
B. Vertebral fracture by x-ray, CT, MRI, or VFA
Renal A. CrCl < 60 cc/min
B. Clinical development of a kidney stone or by imaging (x-ray, ultrasound, or CT)

Abbreviations: MRI, magnetic resonance imaging; CrCl, creatinine clearance.

a

A significant change is defined by a reduction that is greater than the least significant change as defined by the International Society for Clinical Densitometry (11).