Table 1.

Meta-analysis of Sexual, Psychological, and Body Composition Outcomes

Outcome	No. of Studies	No. of Patients	SMD/WMDa	LL 95% CI	UL 95% CI	P Value	I2, %
Sexual outcomes
No. of satisfying sexual episodesb	8	2684	SMD;1.20	0.88	1.51	<.001	0
Frequency of sexual activity	9	2047	SMD;0.29	0.16	0.41	<.001	41
Libido/desire/ interest in sex	17	3288	SMD;0.35	0.19	0.52	<.001	79
Orgasm	15	3019	SMD;0.20	0.09	0.31	<.001	52
Arousal	12	2901	SMD;0.25	0.09	0.41	.002	77
Pleasure/enjoyment of sex	11	2596	SMD;0.31	0.12	0.51	.002	79
Sexual responsiveness	12	3027	SMD;0.29	0.17	0.41	<.001	57
Sexual self-image	8	2655	SMD;0.20	0.05	0.35	.008	70
Sexual or relationship satisfaction	7	303	SMD;0.83	0.28	1.37	.003	87
Sexual concern	8	2668	SMD;0.24	0.033	0.44	.023	85
Psychological outcomes
Personal distress	9	2669	SMD;−0.34	−0.43	−0.24	<.001	30
Anxiety or fear	4	249	SMD;−0.03	−0.23	0.16	.739	0
Depressed mood	5	282	SMD;0.13	−0.06	0.32	.18	0
Bone health outcomes
Spine BMD, g/cm2	4	177	WMD;−0.00	−0.02	0.01	.636	0
Hip BMD, g/cm2	3	134	WMD;0.01	−0.00	0.03	.094	0
Total body BMD, g/cm2	3	120	WMD;0.00	−0.03	0.04	.922	0
Body composition outcomes
Body weight, kg	4	149	WMD;1.17	−0.20	2.54	.095	0
BMI, kg/m2	5	210	WMD;0.25	−0.81	1.30	.647	0

Abbreviations: LL 95% CI, lower limit of 95% CI; UL 95% CI, upper limit of 95% CI.

^aThe difference in means is calculated as TCR minus TFR.

^bResults are presented in WMD.