Table 2.

Meta-analysis of Lipids and Adverse Effect Outcomes

Outcome	No. of Studies	No. of Patients	WMD/RRa	LL 95% CI	UL 95% CI	P Value	I2, %
Lipid profile
Total cholesterol, mg/dL	24	2817	WMD;−8.51	−13.30	−3.71	.001	73
Triglyceride, mg/dL	23	2701	WMD;−15.29	−22.90	−7.67	<.001	68
LDL, mg/dL	21	2697	WMD;2.62	0.24	5.01	.031	19
HDL, mg/dL	22	2719	WMD;−9.11	−12.89	−5.32	<.001	94
Acne and hirsutism
Acne	10	3161	RR;1.62	1.28	2.06	<.001	0
Hirsutism	10	2983	RR;1.45	1.09	1.93	.011	0

Abbreviations: LL 95% CI, lower limit of 95% CI; UL 95% CI, upper limit of 95% CI.

^aThe difference in means is calculated as TCR minus TFR.