Table 1.

Comparative Baseline Data of the Study Groups

Variable	Metreleptin	Placebo	P Value for Between Groupsa
Age, y	26.1 ± 1.4	25.1 ± 1.3	.75
BMI, kg/m2	21.1 ± 0.6	20.1 ± 0.7	.21
Total fat, kg	13.8 ± 0.9	11.8 ± 1.0	.21
Total BMD, g/cm2	1.10 ± 0.03	1.16 ± 0.03	.09
LS BMD, g/cm2	0.92 ± 0.04	0.97 ± 0.03	.22
Total hip BMD, g/cm2	0.91 ± 0.03	0.93 ± 0.04	.79
FN BMD, g/cm2	0.82 ± 0.03	0.83 ± 0.04	.76
Radius BMD, g/cm2	0.57 ± 0.02	0.54 ± 0.01	.37
Es2, pg/mL	23.3 ± 9.6	12.9 ± 1.5	.48
LH, mIU/mL	8.8 ± 3.3	12.8 ± 5.5	.47
FSH, mIU/mL	5.3 ± 0.5	4.6 ± 0.5	.21

Data are presented as mean ± SEM.

^aMann-Whitney test.