Table 3.
Bivariate Correlations at Baseline Between Circulating Study's Parameters in the Sum of Patients With Hypothalamic Amenorrhea
| Variable | iPTH, pg/mL | RANKL, pmol/L | OPG, pmol/L | RANKL to OPG Ratio | Sclerostin, ng/mL | DKK-1, ng/mL | FGF23, U/mL | 25OH VitD, μg/dL |
|---|---|---|---|---|---|---|---|---|
| Leptin, ng/mL | 0.09 (0.73) | −0.12 (0.63) | 0.12 (0.63) | −0.19 (0.44) | −0.43 (0.07) | 0.06 (0.83) | 0.02 (0.95) | 0.23 (0.36) |
| iPTH, pg/mL | 0.52 (0.03) | 0.02 (0.93) | 0.40 (0.10) | −0.27 (0.28) | −0.22 (0.38) | 0.38 (0.12) | −0.07 (0.77) | |
| RANKL, pmol/L | −0.46 (0.05) | 0.94 (<0.001) | 0.01 (0.97) | −0.27 (0.28) | 0.26 (0.29) | −0.14 (0.58) | ||
| OPG, pmol/L | −0.71 (0.001) | −0.40 (0.10) | 0.26 (0.30) | −0.38 (0.12) | −0.01 (0.98) | |||
| RANKL to OPG ratio | 0.23 (0.36) | −0.27 (0.28) | 0.39 (0.11) | −0.16 (0.53) | ||||
| Sclerostin, ng/mL | 0.19 (0.44) | 0.22 (0.37) | −0.32 (0.19) | |||||
| DKK-1, ng/mL | −0.11 (0.68) | −0.10 (0.69) | ||||||
| FGF23, U/mL | 0.15 (0.56) |
Data are presented as Spearman's coefficient of correlation; rs (P value).