Table 3.
Testosterone and Incidence of Clinical Cardiovascular Events
| Testosterone Level | Incident Coronary Heart Disease |
Incident Congestive Heart Failure |
||
|---|---|---|---|---|
| Hazard Ratioa (95% CI) | P Value | Hazard Ratioa (95% CI) | P Value | |
| Quartile 1 | 0.87 (0.60–1.26) | .46 | 0.77 (0.46–1.29) | .32 |
| Quartile 2 | 0.97 (0.69–1.38) | .88 | 0.72 (0.43–1.21) | .22 |
| Quartile 3 | 0.97 (0.69–1.36) | .86 | 0.87 (0.53–1.42) | .58 |
| Quartile 4 | 1.0 | 1.0 | ||
Cut points for testosterone: quartile 1 ≤288.4 ng/dL, quartile 2 = 288.5–377.6 ng/dL, quartile 3 = 377.7–480.1 ng/dL, quartile 4 ≥480.2 ng/dL
a
Multivariable model adjusted for age, race/center, BMI, waist circumference, cigarette smoking, diabetes, hypertension, and LDL and HDL cholesterol.