A and B, Patients with mutations of ARMC5 had massive enlargement of their adrenal glands (dotted red circle) and multiple nodules on their CT scans [A, patient 8 with p.(A702_S706del); B, patient 9 with p.R267X]. C and D, Wild-type patients have smaller adrenal hyperplasia (C, patient 97; D, patient 74).