Table 1. Demographic and clinical characteristics of the primary study participants.
| Total (n = 1672) | Men (n = 999) | Women (n = 673) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAD | Control | OR (95%CI) | P value | CAD | Control | OR (95%CI) | P value | CAD | Control | OR (95%CI) | P value | |
| Number, n | 956 | 716 | 695 | 304 | 261 | 412 | ||||||
| Age, Years (SD) | 70.9 (9.7) | 58.8 (13.7) | <0.001 | 70.4 (9.9) | 60.0 (14.5) | <0.001 | 72.4 (9.0) | 57.9 (13.0) | <0.001 | |||
| Male sex, n (%) | 695 (72.7) | 304 (42.5) | 3.60 (2.94–4.43) | <0.001 | ||||||||
| Obesity, n (%) | 133 (13.9) | 57 (8.0) | 1.87 (1.35–2.59) | <0.001 | 102 (14.7) | 26 (8.6) | 1.84 (1.17–2.89) | 0.007 | 31 (11.9) | 31 (7.5) | 1.66 (0.98–2.80) | 0.075 |
| Hypertension, n (%) | 739 (77.3) | 311 (43.4) | 4.43 (3.59–5.48) | <0.001 | 546 (78.6) | 156 (51.3) | 3.48 (2.60–4.64) | <0.001 | 193 (74.0) | 155 (37.6) | 4.71 (3.35–6.62) | <0.001 |
| Dyslipidemia, n (%) | 702 (73.4) | 388 (54.2) | 2.34 (1.90–2.87) | <0.001 | 498 (71.7) | 169 (55.6) | 2.02 (1.53–2.67) | <0.001 | 204 (78.2) | 219 (53.2) | 3.15 (2.22–4.48) | <0.001 |
| Diabetes mellitus, n (%) | 383 (40.1) | 39 (5.5) | 11.6 (8.20–16.4) | <0.001 | 288 (41.4) | 21 (6.9) | 9.54 (5.97–15.2) | <0.001 | 95 (36.4) | 18 (4.4) | 12.5 (7.33–21.4) | <0.001 |
| Smoking habit, n (%) | 562 (58.8) | 170 (23.7) | 4.58 (3.70–5.68) | <0.001 | 516 (74.2) | 162 (53.3) | 2.53 (1.91–3.35) | <0.001 | 46 (17.6) | 8 (1.9) | 10.8 (5.01–23.3) | <0.001 |
| BMI (kg/m2), mean (SD) | 23.6 (3.6) | 22.9 (2.8) | <0.001 | 23.8 (3.4) | 23.4 (2.6) | 0.057 | 22.9 (3.8) | 22.6 (2.9) | 0.131 | |||
| SBP (mmHg), mean (SD) | 132.4 (20.4) | 126.4 (18.7) | <0.001 | 131.5 (20.4) | 129.4 (17.8) | 0.124 | 134.8 (20.4) | 124.2 (19.1) | <0.001 | |||
| DBP (mmHg), mean (SD) | 73.1 (13.3) | 73.4 (11.8) | 0.651 | 73.0 (13.5) | 76.1 (11.9) | <0.001 | 73.3 (12.9) | 71.4 (11.4) | 0.051 | |||
| TG (mg/dl), mean (SD) | 136.7 (78.8) | 101.1 (63.3) | <0.001 | 140.4 (93.1) | 111.7 (78.6) | <0.001 | 126.8 (64.9) | 93.2 (47.7) | <0.001 | |||
| TC (mg/dl), mean (SD) | 174.3 (36.0) | 202.6 (34.0) | <0.001 | 168.9 (34.4) | 196.2 (32.0) | <0.001 | 188.7 (36.5) | 207.2 (34.8) | <0.001 | |||
| HDL (mg/dl), mean (SD) | 51.4 (14.9) | 61.0 (14.8) | <0.001 | 49.0 (13.8) | 57.8 (14.9) | <0.001 | 58.0 (15.8) | 63.4 (14.3) | <0.001 | |||
| LDL (mg/dl), mean (SD) | 98.0 (28.8) | 121.7 (28.8) | <0.001 | 95.0 (28.2) | 116.7 (27.6) | <0.001 | 105.9 (28.9) | 125.4 (29.1) | <0.001 | |||
| FBS (mg/dl), mean (SD) | 120.7 (45.3) | 94.4 (14.2) | <0.001 | 122.3 (46.2) | 96.6 (17.0) | <0.001 | 116.6 (42.7) | 92.7 (11.5) | <0.001 | |||
| Number of affected vessels | ||||||||||||
| 1 | 377 (39.4) | NA | 265 (38.1) | NA | 112 (42.9) | NA | ||||||
| 2 | 273 (28.6) | NA | 199 (28.6) | NA | 74 (28.3) | NA | ||||||
| 3 | 306 (32.0) | NA | 231 (33.2) | NA | 75 (28.7) | NA | ||||||
The differences in clinical characteristics between patients with CAD and controls were evaluated.
Data are presented as means ± SD or n (%). Continuous variables are expressed as means ± SD. Categorical variables are expressed as percentages.
Abbreviations: BMI, body mass index; CAD; coronary artery disease; CI, confidence interval; DBP, diastolic blood pressure; FBS, fasting blood sugar; HDL, high-density lipoprotein; LDL, low-density lipoprotein; OR, odds ratio; SBP, systolic blood pressure; TC, total cholesterol; TG, triglyceride.