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. 2017 Apr 17;12(4):e0175478. doi: 10.1371/journal.pone.0175478

Fig 1. Structure of 2-hydroxypropyl-β-cyclodextrin (HPβCD) where R = H or CH2-CHOH-CH3.

Fig 1

There are 21 (red) hydroxyl groups on βCD which are potential substitution sites for the condensation reaction with propylene oxide to yield various species of HPβCD with different degrees of substitution depending upon how many sites are substituted.