Table 3.
Inclusion criteria, number of included trials, methods for summarizing study results and main result in three meta-analyses of placebo-controlled trials of homeopathy
Linde et al. (Ref. 42) | Walach (Ref. 43) | Cucherat et al. (Ref. 44) | |
---|---|---|---|
Main differences regarding inclusion criteria | All explicitly randomized and/or double-blind trials with data suitable for meta-analysis | Only randomized trials published in non-homeopathic peer-reviewed journals listed in Medline or Embase | Only randomized trials with a predefined main outcome measure |
Number of trials checked for eligibility | 119 | Unclear | 118 |
Number of trials included in meta-analysis | 89 | 36 | 16 |
Approach to summarizing effect sizes | Combined odds ratio | Standardized effect size | Combination of P values |
Meta-analytic model chosen | Random effects | Random effects | Weighted sum of Zs |
Main result | Significant: OR=2.45 (95% CI 2.05 to 2.93) | Not significant: g=0.259 (95% CI -0.319 to 0.837) | Significant: combined P=0.000036 |
OR=Odds ratio; CI=confidence interval