Table 3. Hazard ratios and 95% confidence intervals for the composite endpoints in IgAN patients with CKD stage 3 with different eGFR.

eGFR (mL/min/per1.73m2)	number	HR(95% CI)	P value
55 to < 60 †	70	1.000	—
50 to <55	77	0.557 (0.225–1.377)	0.205
45 to < 50	63	0.974 (0.380–2.494)	0.955
40 to < 45	67	2.019 (0.950–4.292)	0.068
35 to < 40	58	2.846 (1.330–6.094)	0.007*
30 to < 35	55	7.201 (3.570–14.523)	< 0.001*
P for trend	—	—	< 0.001*

HRs and 95% CIs adjusted for age, sex, systolic blood pressure, diastolic blood pressure and proteinuria. Composite endpoints: doubling of serum creatinine, end-stage renal disease, or all-cause mortality.

*P<0.05.

^† This group served as the reference.

Abbreviations: IgAN, IgA nephropathy; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; HR, hazard ratios.