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. 2017 Apr 17;12(4):e0175825. doi: 10.1371/journal.pone.0175825

Table 4. Risk of fractures for patients with and without post-stroke rehabilitation stratified by sex and age.

Rehabilitation Non-rehabilitation Model 1 Model 2
n§ Fracture cases Person-years Incidence rate* n§ Fracture cases Person-years Incidence rate* aHR
(95% CI)
p value aHR
(95% CI)
p value
Male
Age 2064 1039 25 993.2 2.5 1039 30 991.8 3.0 0.85
(0.50–1.45)
0.549 0.87
(0.51–1.49)
0.618
Age ≥ 65 1440 64 1313.0 4.9 1440 56 1280.0 4.4 1.12
(0.78–1.61)
0.541 1.24
(0.85–1.81)
0.274
Female
Age 2064 476 17 451.7 3.8 476 11 454.9 2.4 1.60
(0.75–3.43)
0.228 1.70
(0.78–3.71)
0.183
Age ≥ 65 1172 119 1026.3 11.6 1172 73 1012.6 7.2 1.62
(1.21–2.17)
0.001 1.82
(1.33–2.50)
<0.001

The propensity score matching procedure was performed after initial stratification for sex and age of the total of “11,806 patients”§ included in this study.

* Per 100 person-years, calculated by correcting immortal time.

Model 1 used a multivariate Cox proportional hazard regression model to adjust for all baseline characteristics listed in Table 1.

Model 2 used a stratified Cox proportional hazard regression model stratified for propensity-score matched groups.

§ After propensity score matching, a total of 8,384 patients were enrolled. However, the values in the table do not add up to 8,384 patients. This is because in order to keep all paired relationships when stratifying sex and age, we stratified sex and age from the initial total 11,806 patients. After stratification, we separately performed propensity score matching in each stratum. Therefore, there are 2078, 2880, 952 and 2344 patients included in each stratum.