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. 2017 Apr 17;12(4):e0175888. doi: 10.1371/journal.pone.0175888

Fig 4. Loss of BIG1 causes cell death of excitatory neurons.

Fig 4

(A-C), Activated Caspase-3 colocalized with Tbr1 (white arrowheads) at (A) E13.5, (B) E15.5 and (C) E17.5 in Arfgef1geo/geo brains. Scale bars, 200 μm; *insets, 50 μm. n = 3 per group. Fro, apoptosis front; Max, maximum apoptosis area.