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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Mol Cell Neurosci. 2017 Feb 14;80:44–51. doi: 10.1016/j.mcn.2017.02.003

Figure 1.

Figure 1

Foxo1 expression in embryonic direct pathway striatal projection neurons. Isl1 fate-map (Isl1cre/+;RosaCAG-tdTomato/+) shows tdTomato expression in direct pathway striatal projection neurons at E15.5 (A) and E18.5 (D). The majority of Foxo1+ cells are observed in Isl1 lineage striatal projection neurons at E15.5 (B–C) and E18.5 (E–F). Foxo1+ neurons are found in a subpopulation of Ebf1+ neurons (G–I) and Foxp1+ neurons at E18.5 (J–K). A selected confocal Z-plane shows Foxo1 protein in both the nucleus and cytoplasm of Foxp1+ developing striatal projections neurons (K). Foxo1 was not found in Nkx2.1+ striatal interneurons at E18.5 (L).