Table 3. PFT results for the patient groups.
| PFT | IgG4-RRD group (n=9) (mean ± SD) | IgG4-RDEI group (n=8) (mean ± SD) | P value |
|---|---|---|---|
| VC | 90.96±13.03 | 94.33±19.97 | 0.664 |
| FVC | 91.67±14.50 | 92.03±21.27 | 0.426 |
| FEV1 | 80.00±14.47 | 91.66±14.59 | 0.469 |
| FEV1/FVC | 72.62±13.06 | 78.59±6.32 | 0.346 |
| PEF | 83.45±23.44 | 86.14±9.58 | 0.828 |
| MEF75 | 70.53±36.13 | 87.89±12.25 | 0.426 |
| MEF50 | 58.11±36.86 | 76.97±26.66 | 0.277 |
| MEF25 | 51.47±31.43 | 67.80±22.52 | 0.218 |
| MMEF75/25 | 54.84±33.64 | 73.91±19.67 | 0.192 |
| RV | 92.11±14.27 | 85.44±17.84 | 0.421 |
| TLC | 91.26±10.54 | 84.00±10.59 | 0.132 |
| RV/TLC | 38.45±3.91 | 39.83±6.52 | 0.228 |
| VA | 91.12±11.17 | 89.67±16.58 | 0.056 |
| DLCO/VA | 72.09±15.56 | 92.19±15.45 | 0.044* |
| DLCO | 65.46±15.39 | 78.77±8.93 | 0.146 |
Data are presented as the percentage of the predicted value except for FEV1/FVC and RV/TLC, which are ratios. DLCO/VA was significantly higher in the IgG4-RDEI group than in the IgG4-RRD group. There were no other significant differences between the two groups (*, indicate significance at the 0.05 level). IgG4-RRD, IgG4-related respiratory disease; IgG4-RDEI, IgG4-related disease extrapulmonary involvement; VC, vital capacity; FVC, forced vital capacity; FEV1, forced expiratory volume in 1 s; PEF, peak expiratory flow; MEF75%, MEF50%, MEF25%, maximum expiratory flow at 75%, 50%, and 25% of FVC; MMEF75/25, maximal mid-expiratory flow; RV, residual volume; TLC, total lung capacity; DLCO, diffusing capacity of the lung for carbon monoxide; VA, alveolar ventilation; DLCO/VA, diffusing capacity of the lung for carbon monoxide per liter of alveolar volume.