Table 1. Treatment characteristics and clinical outcome of the 21 TB patients treated with adjunctive resectional lung surgery in Beijing, China, 1992–2014.
Patient | Sex | Age (yrs) | Category | Radiological results | Surgery | Surgical complication | Resistance profile | Treatment regimen | Outcome |
---|---|---|---|---|---|---|---|---|---|
1 | F | 41 | II | U (RUL) | Lobectomy | None | E, S, Km, Pto, PAS, Am, RFT | Z, Clr, Lfx, PAS, Cm | Cured |
2 | M | 27 | I | U (RUL) | Lobectomy | None | None | E, S, Lfx, Pto, Z | Cured |
3 | M | 40 | III | U (LUL) | Lobectomy | None | S | H, R, E, Z | Cured |
4 | F | 37 | III | U (RUL) | Lobectomy | Lung infection | S | H, R, E, Z | Cured |
5 | M | 30 | I | U (LL destroyed) | Pneumonectomy | None | S | E, Lfx, PAS, Am | Cured |
6 | M | 33 | III | U (LUL) | Lobectomy | None | PAS, Ofx, Lfx, RFT | E, Am, Pto, Mfx | Cured |
7 | M | 37 | I | U (LUL) | Lobectomy | None | E | Z, RFT, PAS, Km | Cured |
8 | M | 32 | III | U (RLL) | Lobectomy | None | E | Pto, PAS, Z, Mfx, E | Cured |
9 | M | 40 | II | U (RUL) | Lobectomy | None | S, Km, Pto, PAS, Ofx | E, Lfx, Am, PAS, RFT | Relapse |
10 | F | 26 | IV | U (LUL) | Lobectomy | None | S, Km, Am, PAS, RFT, Ofx, Lfx | PAS, Cm, E, Mfx, Clr | Relapse |
11 | F | 36 | II | U (LUL) | Lobectomy | Lung infection | S, Km, Pto, Ofx, RFT | PAS, Pto, Lfx, Am | Relapse |
12 | M | 29 | III | U (LLL) | Lobectomy | None | S | H, R, E, Z | Relapse |
13 | M | 17 | I | U (LUL) | Lobectomy | None | E, S | PAS, Pto, Lfx, Am | Relapse |
14 | M | 30 | III | U (LUL) | Lobectomy | None | S, Ofx | RFT, E, Lfx | Relapse |
15 | M | 41 | I | U (RLL) | Lobectomy | Bronchial stump fistula | S, P, Pto | Lfx, Cm, Pto, PAS | Relapse |
16 | M | 32 | IV | U (RUL) | Lobectomy | Bronchial stump fistula | E, S, Km, Cm, Am, Pto, Ofx, Lfx | Z, Pto, Cfz, Clr, Mfx | Relapse |
17 | F | 35 | II | U (LUL) | Lobectomy | Lung infection | E, S, Km, Pto, PAS, Ofx | H, R, E, Z | Died |
18 | M | 41 | IV | U (RL) | Pneumonectomy | NA | S, Km, Cm, Pto, RFT, Ofx, Lfx | E, Clr, PAS, Am | Died |
19 | M | 28 | III | B (large cavity in RUL, small in LUL) | Lobectomy | Lung infection | S, RFT, Pto, PAS, Lfx | E, Z, RFT, Am, Mfx | Died |
20 | M | 44 | III | U (RLL) | Lobectomy | Lung infection | S | H, R, E, Z | Died |
21 | F | 37 | III | U (RUL) | Lobectomy | NA | E, S | PAS, Pto, Lfx, Km | Died |
M, male; F, female. I, not previous treated for MDR-TB; II, previous treated for MDR-TB; III, not previous treated for XDR-TB; IV, previous treated for XDR-TB. U, unilateral cavities; B, bilateral cavities; LL, left lung; RL, right lung; LUL, left upper lobe; LLL, left lower lobe; RUL, right upper lobe; RLL, right lower lobe. E, ethambutol; S, streptomycin; Km, kanamycin; Am, amikacin; Pto, protionamide; PAS, para-aminosalicylic acid; RFT, rifabutin; Ofx, ofloxacin; Lfx, levofloxacin; Cfz, clofazimine; Clr, clarithromycin; Mfx, moxifloxacin.