Kessler et al. (9) |
Prospectively collected clinical data |
n=27; age =61 yr; BMI =40 kg/m2
|
Right-heart catheterization |
Mean PAP >20 mmHg |
59% |
Kauppert et al. (23) |
Prospective cross-sectional study of patients who were on NIV therapy |
n=21; BMI =45 kg/m2; prior to enrollment, patients were treated with NIV for a mean of 1.9 yr. PCO2 and PO2 data prior to NIV were not reported |
Right-heart catheterization |
Mean PAP >20 mmHg |
81% had mild to moderate PH |
Alawami et al. (10) |
A retrospective analysis of dataset |
n=25 |
Transthoracic echocardiography |
Systolic PAP >30 mmHg |
88% |
Sugerman et al. (24) |
Prospective study |
n=26; age =44 yr; BMI not reported; did not use the standard diagnostic criteria for OHS; pre-operative assessment for Bariatric surgery |
Right-heart catheterization |
Mean PAP ≥20 mmHg |
88% |
Held et al. (8) |
Retrospective study |
n=12 (3 of them had co-existing COPD); age =62 yr; BMI =36 kg/m2
|
Right-heart catheterization and transthoracic echocardiography |
Mean PAP at rest ≥25 mmHg or mean PAP at rest <25 mmHg and mean PAP at exercise ≥50 mmHg or, an echocardiographic systolic PAP ≥50 mmHg at rest |
Not reported (mean PAP =49±13 mmHg) |
Marik & Desai (25) |
Retrospective study |
n=61 (77% women and 92% black); age =59 yr; BMI =48.9 kg/m2 |
Transthoracic echocardiography; the peak tricuspid regurgitant velocity was used; to estimate the systolic PAP |
Systolic PAP >35 mmHg; systolic PAP >45 mmHg (moderate to severe PH) |
77%; 41% (moderate to severe PH) |
Current study |
Prospective observational cross-sectional study |
n=77; age =60.5 yr; no prior treatment with NIV |
Transthoracic echocardiography |
Systolic PAP >40 mmHg |
68.8% |