Table 2. Comparison of the characteristics between IMT and IPT groups.
Variable | IMT group (n=9) | IgG4-related IPT group (n=17) | P value |
---|---|---|---|
Age (mean) | 39.22 | 48.82 | 0.031 |
Sex (M/F) | 7/2 | 9/8 | 0.399 |
Symptoms (S/A)† | 7/2 | 13/4 | 0.997 |
Smoking history (yes/never) | 4/5 | 6/11 | 0.692 |
Tumor size (cm) | 3.47 | 2.22 | 0.007 |
Destroyed alveolars | 9 (100%) | 15 (88.24%) | 0.002 |
Totally | 8 (88.89%) | 3 (17.65%) | |
Partially | 1 (11.11%) | 12 (70.59%) | |
Cytological atypia | 2.4–5.0/HPF⬥ (mean 3.5/HPF) | 0.0–2.9/HPF (mean 1.4/HPF) | - |
Obstructive phlebitis | 0 | 7 (41.18%) | 0.058 |
Lymphoid follicles | 0.0–3.0/HPF (mean 1.6/HPF) | 1.0–7.1/HPF (mean 3.0/HPF) | 0.045 |
SMA | 8 (88.89%) | 10 (58.82%) | 0.190 |
IgG+ plasma cells | 34.8-127.0/HPF (mean 74.7/HPF) | 107.3-187.8/HPF (mean 149.1/HPF) | <0.0001 |
IgG4+/IgG+ plasma cells# | 0–50.70% (mean 22.58%) | 52.86–81.63% (mean 68.28%) | - |
ALK-1# | 7 (77.78%) | 0 | - |
OS (%) | 88.89% | 100% | 0.197 |
DFS (%) | 7 (77.78%) | 17 (100%) | 0.056 |
†, S and A represent symptomatic and asymptomatic patients, respectively; ⬥, HPF is short for high-power field; #, due to the fact that cytological atypia, IgG4 and ALK-1 were regard as diagnostic criteria, P values were not calculated.