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. 2017 Mar;9(3):519–528. doi: 10.21037/jtd.2017.02.50

Figure 3.

Figure 3

The expression of TGF-β1, FGF10, and PDGF in INSIP and IPF by immunohistochemistry detection. (A-C) TGF-β1, FGF10, and PDGF were strongly expressed in alveolar epithelial cells (red arrow), vascular endothelial cells (yellow arrow), alveolar macrophages (black arrow) of patients with INSIP (Envison ×200); (D-F) above cytokines also highly expressed in various type of cells in patients with IPF, including bronchial epithelial cells (blue arrow), alveolar epithelial cells (red arrow), vascular endothelial cells (yellow arrow), alveolar macrophages (black arrow) (Envison ×200); (G-I) the expression of TGF-β1, FGF10 and PDGF in normal lung tissues (Envison ×200). TGF-β1, transforming growth factor-beta-1; FGF10, fibroblast growth factor 10; PDGF, platelet derived growth factor; INSIP, idiopathic nonspecific interstitial pneumonia; IPF, idiopathic pulmonary fibrosis.