Table 1.

Mean change in plasma total cholesterol, unesterified (free) cholesterol and esterified cholesterol following intravenous infusion of CER-001 into fasted rabbits allowed free access to food after 8 h

Measure/time (h)	CER-001 (mg/kg)
	Placebo	2.5	5.0	10.0	20.0
Total cholesterol
30	−0.286	−0.137	0.047	−0.029	0.046
34	−0.274	−0.149	0.017	−0.173	−0.090
Free cholesterol
30	−0.038	−0.007	0.039	0.086	0.068
34	−0.049	−0.023	0.006	−0.005	−0.001
Cholesterol ester
30	−0.248	−0.130	0.008	−0.115	−0.022
34	−0.225	−0.126	0.011	−0.168	−0.089

Baseline values were subtracted to determine the change in cholesterol levels. Baseline total cholesterol: 0.41–1.08 g/L; unesterified cholesterol: 0.13–0.3 g/L; esterified cholesterol 0.28–0.78 g/L