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. 2017 Apr 18;11:209. doi: 10.3389/fnins.2017.00209

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Copyright © 2017 Xu, Tang, Pan, Xie, Zhang, Ji, Yang, Zhou and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immunofluorescence staining to detect ROS in the prefrontal cortex. (A) Representative images of CD11b (green) and 8-OH-dG (red) in the prefrontal cortex. (B) SNI significantly increased fluorescence intensity of CD11b and 8-OH-dG in the prefrontal cortex, which was attenuated by minocycline. (Scale bar = 50 μm). The data are expressed as the mean ± SEM of 4 rats in each group. ^*P < 0.05 compared to the Sham group, ^#P < 0.05 compared to the SNI group. DAPI staining is shown in blue.