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. 2017 Apr 10;8:15016. doi: 10.1038/ncomms15016

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Copyright © 2017, The Author(s)

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(a) Electron microscope scanning of exosomes isolated from human serum. (b) Sr-exosome EGFR is related to the progression of GC. Exosomes were isolated from serum of healthy donors (NC), stage II/III GC patients and stage IV GC patients, respectively (n=20); Alix, TSG101 and CD63 were used as the internal control of exosomes. (c) The expression of HGF, c-MET and p-c-MET in para-carcinoma tissue (liver) and GC liver metastases (n=5). (d) Immunohistochemistry (IHC) analysis of HGF in GC liver metastasis. (e) Positive ratio of HGF and its receptor c-MET in GC liver metastases (n=30). The data represent the mean±s.e.m. *P< 0.05, **P<0.01 (Student's t-test).