Figure 6. Loss of BabA expression in mice occurs even in the absence of capacity to bind Le^b.

Female Le^b transgenic FVB/N mice and their WT littermates were inoculated with BabACL2_8CT:9CT or J166_8CT:7CT and sacrificed 2 weeks PI. Colonization density (a) and selection for loss of BabA expression (b) were similar in WT and Leb mice inoculated with J166 and BabACL2, which expresses BabA but does not attach to Leb. No significant differences were found between any of the experimental groups.