Table 3. Serum cytokine and nitric oxide levels in patients grouped by the number of variant TLR genotypes.

		TNF-α (pg/mL)	IL-6 (pg/mL)	NOx (nmol/mL)
Wildtype TLRs	n = 16	16.5 ± 7.9	18.4 ± 9.1	67.4 ± 18.5
One variant TLR	n = 46	11.5 ± 6.8*	13.7 ± 7.5	56.0 ± 23.7
Two variant TLRs	n = 42	7.8 ± 3.8*	10.3 ± 3.9*	55.8 ± 19.5*
Three variant TLRs	n = 10	2.8 ± 2.5*	8.5 ± 1.4*	33.6 ± 17.1*

TNF-α: tumor necrosis factor alpha; IL: interleukin; NOx: nitric oxide metabolites; *p < 0.01 compared with wildtype TLRs.