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. 2017 Apr 14;23(14):2493–2504. doi: 10.3748/wjg.v23.i14.2493

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©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.

This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.

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Diffuse large B-cell lymphoma. A 63-year-old woman presented with epigastralgia. A and B: Contrast-enhanced computed tomography (CT) scan showing diffuse, homogeneous gastric wall thickening with a smooth well-defined outer wall (arrow). An 83-year-old woman presented with tarry stool and constipation for a week; C and D: Post-contrast-enhanced CT revealing wall thickness (arrow) at the gastric body and several enlarged lymph nodes in the mesentery and para-aortic retroperitoneum (stars); E: Low-power photomicrograph (original magnification, × 20; HE stain) showing diffuse proliferation of large monomorphic neoplastic cells with abundant cytoplasms; F: The neoplastic cells occupy the full thickness of the submucosa (star).