Table 5.
Univariate Cox analysis of the impact of various characteristics on patient survival
| Characteristics |
DFS |
P value |
OS |
P value | ||
| HR | 95%CI | HR | 95%CI | |||
| Sex | ||||||
| Male vs Female | 0.91 | 0.42-1.65 | 0.800 | 0.93 | 0.41-2.09 | 0.860 |
| Age (yr) | ||||||
| < 60 vs ≥ 60 | 0.80 | 0.40-1.62 | 0.530 | 1.05 | 0.50-2.19 | 0.910 |
| BMI | ||||||
| < 25 vs ≥ 25 | 0.22 | 0.05-0.93 | 0.039 | 0.26 | 0.06-1.11 | 0.069 |
| Tumor size (cm) | ||||||
| ≤ 3 vs > 3 | 1.23 | 0.60-2.51 | 0.570 | 0.98 | 0.46-2.08 | 0.960 |
| Tumor grade | ||||||
| 1 vs 2, 3 | 1.08 | 0.47-2.50 | 0.850 | 0.96 | 0.41-2.26 | 0.930 |
| cTNM | ||||||
| II vs III | 2.23 | 0.92-5.41 | 0.075 | 1.96 | 0.80-4.80 | 0.144 |
| CEA (ng/mL) | ||||||
| < 5 vs ≥ 5 | 0.91 | 0.46-1.81 | 0.790 | 0.72 | 0.34-1.51 | 0.390 |
| CA199 (U/mL) | ||||||
| < 35 vs ≥ 35 | 1.77 | 0.77-4.08 | 0.180 | 1.30 | 0.50-3.40 | 0.600 |
| CRT efficacy | ||||||
| Poor vs good | 0.43 | 0.19-0.95 | 0.036 | 0.55 | 0.24-1.24 | 0.150 |
| ypTNM | ||||||
| ypcr, I,II vs III | 1.61 | 1.14-2.27 | 0.006 | 1.46 | 1.01-2.11 | 0.045 |
| Adjuvant CT | ||||||
| Non vs yes | 0.69 | 0.30-1.60 | 0.390 | 0.60 | 0.25-1.40 | 0.240 |
| EOU | ||||||
| Non vs yes | 1.17 | 0.59-2.31 | 0.660 | 1.13 | 0.54-2.37 | 0.750 |
| EOG | ||||||
| Non vs yes | 0.30 | 0.90-0.97 | 0.044 | 0.37 | 0.11-1.23 | 0.110 |
EOU: Eligible OME users; Non-EOU: Non-eligible OME users; EOG: Effective OME group; Non-EOG: Non-effective OME group; BMI: Body mass index; Adjuvant CT: Adjuvant chemotherapy.