Table 3. Univariate logistic regression analysis of clinical and laboratory parameters, and 3-month mortality.
| Variable | Category | OR (95% CI) per 1 SD | p-value | Events |
|---|---|---|---|---|
| Age (years) | 1.37 (0.94–2.08) | 0.114 | 40/146 | |
| Sex | male | Ref. | 16/70 | |
| female | 1.56 (0.75–3.30) | 0.239 | 24/76 | |
| BMI (kg/m2) | 0.70 (0.47–1.02) | 0.074 | 40/146 | |
| Hypertension | no | Ref. | 7/16 | |
| yes | 0.44 (0.15–1.31) | 0.128 | 33/130 | |
| Type 2 Diabetes Mellitus | no | Ref. | 21/69 | |
| yes | 0.76 (0.36–1.58) | 0.465 | 19/76 | |
| MAP (mmHg) | 0.56 (0.36–0.84) | 0.007 | 40/146 | |
| NYHA class | 2 and 3 | Ref | 20/90 | |
| 4 | 1.94 (0.93–4.09) | 0.078 | 20/56 | |
| EF (%)* | >40 | Ref | 14/71 | |
| ≤40 | 1.44 (0.65–3.26) | 0.373 | 17/65 | |
| Total cholesterol (mmol/L) | 0.53 (0.33–0.80) | 0.005 | 40/146 | |
| LDL-c (mmol/L) | 0.56 (0.34–0.85) | 0.011 | 40/146 | |
| HDL-c (mmol/L) | 0.69 (0.43–1.05) | 0.107 | 40/146 | |
| Triglycerides (mmol/L) | 0.74 (0.46–1.10) | 0.172 | 40/146 | |
| Large VLDL-p (nmol/L) | 0.43 (0.15–0.91) | 0.066 | 20/74 | |
| Total LDL-p (μmol/L) | 0.68 (0.44–1.02) | 0.075 | 37/130 | |
| Large LDL-p (μmol/L) | 0.63 (0.38–0.98) | 0.057 | 34/121 | |
| Small LDL-p (μmol/L) | 0.89 (0.58–1.30) | 0.561 | 36/127 | |
| Total HDL-p (μmol/L) | 0.38 (0.23–0.60) | <0.001 | 37/130 | |
| Large HDL-p (μmol/L) | 1.22 (0.79–1.88) | 0.353 | 30/103 | |
| Small HDL-p (μmol/L) | 0.35 (0.19–0.60) | <0.001 | 27/110 | |
| GFR (ml/min/1.73 m2) | 0.60 (0.39–0.88) | 0.012 | 39/145 | |
| Creatinine (mol/L) | 1.44 (1.02–2.06) | 0.039 | 39/145 | |
| Urea (mmol/L) | 1.61 (1.13–2.39) | 0.013 | 39/145 | |
| NT-proBNP (pg/mL) | 1.92 (1.32–2.93) | 0.001 | 38/135 | |
| CRP (μg/mL) | 1.18 (0.83–1.68) | 0.341 | 40/145 |
For continous variables ORs are presented per standard deviation increment. Significant associations are depicted in bold. BMI = Body Mass Index; CI = confidence interval; CRP = C-reactive protein; EF = Ejection Fraction; Events = number of events/total number of patients in category; GFR = glomerular filtration rate; HDL-c = high density lipoprotein cholesterol; HDL-p = HDL particle concentration; LDL-c = low-density lipoprotein cholesterol; LDL-p = large LDL particle concentration; n = number of samples in which particular parameter was analysed; MAP = Mean Arterial Pressure; NT-proBNP = N-terminal pro-Brain Natriuretic Peptide; NYHA = New York Heart Association Functional Classification; OR = odds ratio; Ref. = reference category; SD = standard deviation; VLDL-p = very low-density lipoprotein particle concentration.