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. 2017 Apr 18;7:46601. doi: 10.1038/srep46601

Table 3. Meta-analysis of the association between LMR and clinicopathological features of HCC.

Characteristics No. of studies No. of patients OR (95% CI) p Heterogeneity
I2 (%) Ph
Gender (male vs. female) 3 913 1.16 (0.64–2.09) 0.62 54 0.11
AFP (>400 ng/mL vs. <400 ng/mL) 2 660 1.61 (0.81–3.20) 0.17 73 0.05
Liver cirrhosis (yes vs. no) 3 913 1.66 (0.97–2.83) 0.06 52 0.12
Differentiation (low vs. moderate/high) 3 913 1.04 (0.74–1.46) 0.82 0 0.88
Tumor number (multiple vs. single) 2 660 0.96 (0.62–1.50) 0.87 0 0.61
Tumor size (>5 cm vs. <5 cm) 3 913 1.36 (0.79–2.35) 0.27 69 0.04
TNM stage (III-IV vs. I-II) 2 703 1.78 (1.19–2.68) 0.005 33 0.29
BCLC stage (B/C vs. A) 2 703 1.70 (1.21–2.39) 0.002 0 0.38
Vascular invasion (pos vs. neg) 2 660 1.47 (0.48–4.49) 0.50 84 0.01