Table 2.
Postmatching Follow-Up: Statin Therapy Treatment Patterns Among Statin Users in Statin Benefit Group 1
| Postindex treatment patterns | High-intensity statin initiators (N = 16,793) | Low-/moderate-intensity statin initiators (N = 16,964) | P value |
|---|---|---|---|
| Index medication groups, N (%) | |||
| Atorvastatin | 11,957 (71.2) | 3902 (23.0) | <.001 |
| Rosuvastatin | 2163 (12.9) | 1412 (8.3) | <.001 |
| Simvastatin | 2673 (15.9) | 8953 (52.8) | <.001 |
| Others | 0 (0) | 2697 (15.9) | <.001 |
| Discontinuation, N (%) | 13,618 (81.1) | 13,906 (82.0) | .037 |
| PDC, mean (SD) | 0.5 (0.35) | 0.5 (0.35) | .008 |
| Adherence (PDC ≥80%), N (%) | 4534 (27.0) | 4471 (26.4) | .181 |
| Switching to a nonindex statin with similar intensity, N (%) | 1749 (10.4) | 3177 (18.7) | <.001 |
| Switching to a nonindex statin with different intensity, N (%) | 4789 (28.5) | 2792 (16.5) | <.001 |
| Switching to combination statin therapy and/or nonstatin lipid-lowering therapy, N (%) | 2139 (12.7) | 1857 (10.9) | <.001 |
| Restart, N (%) | 6209 (37.0) | 5813 (34.3) | <.001 |
PDC indicates proportion of days covered; SD, standard deviation.