Table 4.

Brain regions showed altered FC in asthmatic patients before and after GCBT.

Peak area	BA	Side	MNI coordinates			voxels Number	Peak t-value
			X	Y	Z
FC OF LEFT vAI
Cerebellum Posterior Lobe	−	L	−33	−75	−39	41	−15.5062
Temporal lobe	20	R	63	−18	−24	22	−11.5868
Anterior cingulate cortex	32	R	3	45	3	17	−7.6196
Anterior cingulate cortex	32	R	9	33	0	8	4.3224
Parietal lobe	43	R	54	−18	21	10	−9.0851
Parietal lobe	7	L	−15	−66	57	17	−5.354
Postcentral gyrus	2	R	39	−36	42	49	−19.721
Postcentral gyrus	3	L	−12	−39	72	12	−6.7005
Precuneus	7	R	36	−45	51	68	−12.4624
Precentral gyrus	4	L	−21	−24	72	11	−8.0639
FC OF LEFT PI
Medial frontal gyrus	9	L	−9	45	30	36	−9.9896
FC OF RIGHT vAI
Caudate	−	R	12	9	15	4	−5.1337
Putamen	−	L	−24	3	3	23	−7.1454
FC OF RIGHT dAI
Calcarine	30	L	−18	−57	6	4	−5.1478
Calcarine	30	L	−9	−72	15	26	−7.9788

Threshold was set at P < 0.005 (AlphaSim-corrected, cluster size > 189/81/108/108 mm³ for left vAI, left PI, right vAI, right dAI respectively). X, Y, Z, coordinates of primary peak locations in the MNI space.

GCBT, group cognitive behavior therapy; MNI, Montreal Neurological Institute space; FC, functional BA, Brodmann area; R, right; L, left; B, bilateral; vAI, ventral anterior insula; dAI, dorsal anterior insula; PI, posterior insula.