2D molecular interaction mode diagrams of DENV NS2B-NS3pro domain with the bound ligands, a eriodictyol 7-O-glucuronide, b luteolin 8-C-beta-glucopyranoside, c (-)-epicatechin-3-O-gallate, d 6-O-trans-p-coumaroylgeniposide and e luteolin-7-O-glucoside. In all the figures, dashes represent hydrogen bonds while arcs represent hydrophobic interactions. Other highlights: carbon—C; oxygen—O; nitrogen—N