Table 1.

European Neuroendocrine Tumor Society and American Joint Committee on Cancer TNM grading systems for pancreatic tumors[38,39]

	ENETS	AJCC
T Grade (primary tumor)
Tx	Primary tumor is not assessed	Primary tumor is not assessed
T0	No finding of primary tumor	No finding of a primary tumor
Tis		In situ carcinoma
T1	Tumor is limited to the pancreas and < 2 cm	Tumor is limited to the pancreas and ≤ 2 cm
T2	Tumor is limited to the pancreas and 2 to 4 cm	T2 tumor is limited to the pancreas and > 2 cm
T3	Tumor is limited to the pancreas and > 4 cm or with positive duodenum or biliary tract invasion	Tumor has progressed beyond the pancreas but there is no celiac or mesenteric artery involvement
T4	Tumor has invaded the neighboring organs (stomach, spleen, colon, adrenal gland) or walls of the large vessels (celiac artery or superior mesenteric artery)	Tumor shows celiac or superior mesenteric artery involvement
N-lymph node status
Nx	Regional lymph nodes are not assessed	Regional lymph nodes are not assessed
N0	No regional lymph node metastasis	No regional lymph node metastasis
N1	Regional lymph node metastasis is positive	Regional lymph node metastasis is positive
M-distant metastasis
Mx	Distant metastasis is not assessed
M0	No distant metastasis	No distant metastasis
M1	Distant metastasis is positive	Distant metastasis is positive
Stage
0		Tis, N0, M0
I	T1, N0, M0
IA		T1, N0, M0
IB		T2, N0, M0
IIA	T2, N0, M0	T3, N0, M0; T1, N1, M0
IIB	T3, N0, M0	T2, N1, M0; T3,N1,M0
III		T4, Any N, M0
IIIA	T4, N0, M0
IIIB	Any T, N1, M0
IV	Any T, Any N, M1	Any T, Any N, M1