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. 2017 Jan 15;144(2):313–320. doi: 10.1242/dev.135798

Fig. 4.

Fig. 4.

Effect of MKX knockdown or Mkx overexpression on gene expression patterns of human PDL fibroblasts. (A) Analysis of MKX expression in hPDL fibroblasts at passage 7 (P7) and HEK293T as a negative control (n=3 each). (B) Expression of the PDL-related genes in MKX-knockdown hPDL fibroblasts (n=6 each). (C) Expression of FLAG-Mkx in hPDL fibroblasts determined by western blot analysis (left), expression of PDL-related extracellular matrix proteins (center) (n=6) and osteogenic genes in control or FLAG-Mkx-expressing hPDL fibroblasts (right) (n=6). (D) Schematic diagram of Mkx function in PDL homeostasis. All data are mean±s.e.m.; *P<0.05, **P<0.01, ***P<0.001.